Skin Infection Models
Human skin is generally colonized by a well-balanced myriad of microorganisms. In unbalanced situations however, overgrowth of specific microorganisms on either intact or wounded skin can cause problems for patients and their environment. Especially in severely ill hospitalized patients, bacterial skin infections are notorious for their devastating effects. To study the human skin as a reservoir for micro-organisms and to test the potential of skin infection treatments, Biomimiq offers human skin equivalents (HSEs) colonized with relevant skin infections, in collaboration with the Department of Infectious Diseases of the Leiden University Medical Center in Leiden, the Netherlands.
Modulating various skin infections
Biomimiq’s HSEs allow for colonization with the microorganism of your interest, ranging from antibiotic resistant bacteria (e.g. methicillin resistant Staphylococcus aureus (MRSA) and Pseudomonas aerigunosa), yeast or parasites. Bacterial infections can be mimicked on HSEs in planktonic or biofilm settings. A large variety of treatment options can be tested, including application of formulated compounds or exposure to radiation and gases.